Magnetoencephalography MEG Scanner & Super Microscopes to understand Frontotemporal dementia
Dementia Research Charity Chatathon
12/09/22
•27m
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Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Anna Sanchez Avila, PhD Student from University of Dundee and Rebecca Williams, PhD Student in the MRC Cognition & Brain Sciences Unit at University of Cambridge.
Anna Sanchez Avila - I work in the field of motor neuron disease and frontotemporal dementia, which have more in common than you might think. I use high-resolution microscopy techniques to look at how synapses - small, delicate structures that allow our brain cells to communicate with each other - change in disease. I want to also see if those changes happen all over the brain or in specific regions that correlate with the symptoms we see.
Rebecca Williams - I study apathy in conditions associated with frontotemporal degeneration, using a combination of Magnetoencephalography (MEG) imaging, Bayesian frameworks (The Bayesian framework uses metered data to infer the most likely distribution of the modeling parameters) and computational modelling.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia. Raising money for research and providing insights into the latest research taking place across the UK and Worldwide.
This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
Previous Episode
Genomics and Big Data to find new Dementia Medicines & help Diagnosis
December 9, 2022
•24m
Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Dr Danielle Newby, Postdoctoral Data Scientist and Dr Laura Winchester, Alzheimer's Research UK Fellow both from University of Oxford.
Dr Danielle Newby - Based within the Centre for Statistics in Medicine at Oxford. One of my areas of research is now generating evidence about the safety of medicines in people living with dementia and parkinson's disease across the UK and Europe using real world evidence (i.e. medical records). This evidence can be used to help improve decision making by clinicians about the drugs they prescribe and utimately improve the quality of life of these patients.
Dr Laura Winchester - I am interested in the application of large-scale multi-omics data to better understand disease variants and therapeutics. This involves using genomic and proteomic data analysis from Alzheimer’s Disease, Parkinson’s Disease and healthy population cohorts to develop new biomarkers and understand dementia mechanisms by applying integrative and machine learning methodologies. I use all these informatics approaches in my main research focus: the study of the relationship between iron homeostasis and dementia.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia. Raising money for research and providing insights into the latest research taking place across the UK and Worldwide.
This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
Next Episode
Meet the Leading UK Dementia Research Charities
December 9, 2022
•28m
Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Jacqueline Cannon, CEO of The Lewy Body Society, Bridget Barker, CEO of Race Against Dementia, Dr Sara Imarisio, Head of Strategic Initiatives at Alzheimer's Research UK and Katherine Gray, Research Communications Manager at Alzheimer's Society.
Jacqueline Cannon - I'm the CEO of The Lewy Body Society. As a small charity, everyone has more than one job, my role is varied and involves but not limited to: Book keeping; website updates; fulfilment of orders from the society’s online shop; social media updates; taking calls from carers; responding to emails; sending out information packs; managing research grant applications; arranging and taking part in zoom events. We're proud to have a dedicated community of fundraisers and researchers, and bringing them together to support people living with Lewy Bodies is very important.
Bridget Barker - I run the charity started by Formula 1 World Champion Sir Jackie Stewart. On I day-to-day basis this includes ensuring there is appropriate governance, fundraising, marketing, arranging various events and using the charity’s money to support the RAD Fellows’ Development Programme as well as investing in innovative projects to accelerate research into dementia. My maternal grandmother had dementia, and I share in Sir Jackie's passion to find new ways to beat dementia, learning from other industries who are able to bring rapid innovation and new ideas.
Dr Sara Imarisio - I'm the Head of Strategic Initiatives at Alzheimer’s Research UK. I am responsible for overseeing initiatives such as the charity’s Drug Discovery Alliance, the UK Dementia Research Institute, and the Brains for Dementia Research. Prior to joining Alzheimer’s Research UK, I was a postdoc in Cambridge affiliated to Prof David Rubinsztein’s lab, screening for modifiers of neurodegenerative diseases caused by aggregate-prone proteins. I completed my PhD in Italy, working on the characterisation of a protein involved in the latest stages of the cell cycle and necessary for the correct development of the brain.
Katherine Gray - I work in the wonderful Research Communications team at Alzheimer’s Society sharing research updates to the Society’s donors and supporters, sharing research findings through the Society’s channels and in the media. Talking directly to the dementia research community about how the Society can support you.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia. Raising money for research and providing insights into the latest research taking place across the UK and Worldwide.
This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
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