Epigenetics, Exploring Dark crevices of Genes and links to Alzheimer's
Dementia Research Charity Chatathon
01/12/23
•28m
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On the 7th September 2020, Adam Smith hosted the Dementia Research Chatathon LIVE - to share information on the wide variety of research taking place across the world, and the raise money for Alzheimer's Research UK. Please continue to donate and help Adam meet his £5,000 target - details can be found at www.chatathon.uk.
In a way that everyone can understand, this video features Adam talking with:
Professor Katie Lunnon, Professor of Dementia Genomics, University of Exeter. Katie works in the field of epigenetics and gene regulation. Her studies look in the brain to see if we can identify epigenetic differences in individuals with dementia as well as in the blood with the hope of identifying new biomarkers. Initially focusing on Alzheimer's disease but now expanding her studies to look at other dementias as well. Additionally Katie leads a number of functional studies, exploring proteins, iPSCs and gene editing in cell lines - @katielunnon
Dr Leonidas Chouliaras, Clinical Lecturer in Old Age Psychiatry, University of Cambridge. Leo is a clinician and epigeneticist, focused on Lewy Body Dementia. Working both on clinical cohorts, studying DNA methylation in blood samples as well as in autopsy brain tissues, isolating neurons with Lewy Bodies using laser-microdissection and comparing the epigenetic profiles with healthy looking neurons from the same donor or from controls - @chouliarasL
Previous Episode
The role of the Arts and Technology to support Wellbeing in Dementia
January 12, 2023
•27m
On the 7th September 2020, Adam Smith hosted the Dementia Research Chatathon LIVE - to share information on the wide variety of research taking place across the world, and the raise money for Alzheimer's Research UK. Please continue to donate and help Adam meet his £5,000 target - details can be found at www.chatathon.uk.
In a way that everyone can understand, this video features Adam talking with:
Brendan Commane, PhD student, Royal College of Art, London. Brendan is researching the environment in care homes for people with dementia. He is using technology to support a more engaging and stimulating environment and also researching the power of soft toys or a textile item as a means of comfort, security and conversation. He hopes to bring the soft item and the technology together. His is just getting started, however it will involve family, carers and the residents all working together and inclusively - @BGC210.
Dr Kat Algar-Skaife, Postdoctoral Fellow in Dementia Care and Welfare Technology, Norwegian University of Science and Technology (NTNU). Over the past twelve years, I have led and contributed to research around understanding and improving support; developing and evaluating psychosocial, physical activity, and creative interventions. I collaborate with organisations such as Age Cymru and local authorities to ensure that my research has a real-life impact outside of an academic setting. I currently lead the SENSE-Emotion project which aims to provide a deeper understanding of the experiences and emotional responses of people living with dementia engaging with SENSE-GARDEN, an immersive digital sensory room - @kat_algar.
Professor Marion Lynch, Visiting Professor of Dementia Care, University of West London. Marion works on developing the frameworks informing how we think about designing dementia care and in particular how the arts can help - @drmarionlynch.
Next Episode
Getting behind some of the Causes of Dementia - Sleep, Diet, Genes and more
January 13, 2023
•26m
On the 7th September 2020, Adam Smith hosted the Dementia Research Chatathon LIVE - to share information on the wide variety of research taking place across the world, and the raise money for Alzheimer's Research UK. Please continue to donate and help Adam meet his £5,000 target - details can be found at www.chatathon.uk.
In a way that everyone can understand, this video features Adam talking with:
Dr Christina Toomey, Post-doctoral Research Associate, University College London. Christina's research focuses on the proteomics and lipidomics of neurodegenerative diseases and the link to the pathology present. My PhD was on the role TREM2 Gene plays in neurodegeneration too - @christina_neuro.
Dr Guliz Ozcan, Postdoctoral Research Associate, University College London. Guliz works at the interception of sleep and Alzheimer's disease. Sleep problems are one of the earliest symptoms of AD and often arise years before the cognitive deficits. Using zebrafish, we have recently shown that Aβ acutely and reversibly enhances or suppresses sleep as a function of oligomer length - @guilizozcan.
Dr Gemma Lace, Senior Lecturer in Biomedical Science & Lead of Public Engagement and Outreach, University of Salford. Gemma researchers the role of autophagy impairments in Alzheimer's disease and frontotemporal dementia, the role of obesity in dementia risk and how exosomes may shed light on underlying disease mechanisms and be used as diagnostic biomarkers. A large part her job is to also raise dementia awareness through outreach and public engagement events - @gemmalace
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