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The Gastro Girl Podcast - Ozempic, Wegovy, Mounjaro: How They Affect Your Gut
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Ozempic, Wegovy, Mounjaro: How They Affect Your Gut

The Gastro Girl Podcast

07/22/25

49m

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GLP-1 medications like Ozempic (semaglutide), Wegovy, and Mounjaro (tirzepatide) have transformed treatment for type 2 diabetes and weight loss — but they can also cause digestive side effects like nausea, diarrhea, constipation, bloating, and stomach pain that leave many patients confused or worried.

In this episode, we're joined by Dr. Catherine Hudson from LSU Health New Orleans to separate fact from fiction and provide clear, evidence-based guidance. Dr. Hudson breaks down:

  • How GLP-1 receptor agonists work
  • Common digestive side effects—and how to manage them
  • Why lifestyle changes still matter
  • What you need to know before surgery or GI procedures when taking these medications

Whether you're a patient, caregiver, or healthcare provider, this episode offers practical insights to help you navigate the GLP-1 journey with confidence.

This episode is presented in collaboration with the American College of Gastroenterology's Patient Care Committee.

Previous Episode

IBS-C (Irritable Bowel Syndrome with Constipation) is a chronic condition that disrupts how your gut works—causing abdominal pain, bloating, and infrequent, hard-to-pass stools. It can seriously impact your quality of life, and finding the right treatment is often a journey filled with ups and downs.

So, how do you get relief from IBS-C symptoms without feeling like you're back at square one?

In this episode, we welcome back Dr. Bryan Curtin, Director of The Center for Neurogastroenterology and GI Motility at The Melissa L. Posner Institute for Digestive Health & Liver Disease at Mercy Medical Center in Baltimore, MD. Together, we discuss:

  • Why managing IBS-C often requires some trial and error
  • What to do when progress isn't perfect
  • Signs it might be time to adjust your treatment plan
  • Practical tips to prepare for your next appointment—so you can have more productive conversations with your provider

This episode is made possible with support from Ardelyx.

Next Episode

Get ready for a tail-wagging adventure! Oliver Super Beardie, our fearless furry hero and member of the Woof Chat Kids, is back on the case—this time to solve a mysterious throat trouble affecting his buddy Sam. Why is swallowing so hard? What's causing the pain? Oliver's on the trail... and he's sniffing out answers!.

Joining Oliver is brilliant expert guest Dr. Sophia Patel, a leading Pediatric Gastroenterologist from Cleveland Clinic. Together with host Jacqueline Gaulin, they'll follow the clues to uncover what's really going on inside Sam's esophagus—and introduce kids (and grown-ups!) to a condition called Eosinophilic Esophagitis (EoE).

You'll learn what symptoms to watch for, how EoE is diagnosed, and what steps can help kids like Sam feel better—all in a fun, kid-friendly way that mixes science and heart.

A huge shout-out to the incredible John Kennedy, the puppeteer and voice behind Oliver Super Beardie, whose creativity and heart make every episode unforgettable.

This special episode is brought to you by Dupixent.

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