The Medical Matchmaking Machine
Radiolab
08/22/25
•61m
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As he finished his medical school exam, David Fajgenbaum felt off. He walked down to the ER and checked himself in. Soon he was in the ICU with multiple organ failure. The only drug for his condition didn’t work. He had months to live, if that. If he was going to survive, he was going to have to find his own cure. Miraculously, he pulled it off in the nick of time. From that ordeal, he realized that our system of discovering and approving drugs is far from perfect, and that he might be able to use AI to find dozens, hundreds, even thousands of cures, hidden in plain sight, for as-yet untreatable diseases.
EPISODE CREDITS:
Reported by - Latif Nasser
Produced by - Maria Paz Gutiérrez
with mixing help from - Jeremy S. Bloom
Fact-checking by - Natalie A. Middleton
VISIT:
Everycure.org (https://www.everycure.org)
EPISODE CITATIONS:
Books -
Blair Bigham - Death Interrupted: How Modern Medicine is Complicating the Way We Die
David Fajgenbaum - Chasing My Cure, (https://davidfajgenbaum.com/)
Radiolab | Lateral Cuts:
Check out Death Interrupted (https://radiolab.org/podcast/death-interrupted), a conversation with Blair Bigham about a worldview shifting change of heart.
The Dirty Drug and the Ice Cream Tub (https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub) to hear the crazy story about how Rapamycin was discovered.
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Previous Episode
Weighing Good Intentions
August 15, 2025
•24m
In an episode first released in 2010, then-producer Lulu Miller drives to Michigan to track down the endangered Kirtland’s warbler. Efforts to protect the bird have lead to the killing of cowbirds (a species that commandeers warbler nests), and a prescribed burn aimed at creating a new habitat. Tragically, this burn led to the death of a 29-year-old wildlife technician who was dedicated to warbler restoration. Forest Service employee Rita Halbeisen, local Michiganders skeptical of the resources put toward protecting the warbler, and the family of James Swiderski (the man killed in the fire), weigh in on how far we should go to protect one species.
EPISODE CREDITS:
Reported by - Lulu Miller
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Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.
Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.
Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
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Next Episode
Music Hat
August 29, 2025
•31m
With this episode, we’re putting on our music hat. For a program that relies so much on scoring and sound, it’s not often we talk about the musicians and the music they make that inspire us. Today, that changes. Today, we bring you two stories. Each about musicians that our former host and creator of Radiolab, Jad Abumrad, loves.
We originally released these stories many years ago, and both start deep in music itself. Then quickly, they dig deeper — into our relationships with technology, and ourselves.
We start with the band Dawn of Midi, who straddle the intersection between acoustic and electronic sounds. Jad talks to the band about their album, Dysnomia, and how it's filled with heavily-layered rhythms that feel both mechanistic and deeply human, at the same time.
Then, Jad talks with Juana Molina, an Argentine singer who accidentally became a famous actress, when all along all she really wanted was to be a musician.
Special thanks to Dawn of Midi and Juana Molina.
EPISODE CREDITS:
Reported by - JAD ABUMRAD
EPISODE CITATIONS:
Check out Dawn of Midi at dawnofmidi.com and Juana Molina at juanamolina.com
Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!
Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.
Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.
Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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