
The Interstitium
Radiolab
11/17/23
•57m
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In this episode we introduce you to a part of our bodies that was invisible to Western scientists until about five years ago; it’s called "the interstitium," a vast network of fluid channels inside the tissues around our organs that scientists have just begun to see, name, and understand. Along the way we look at how new technologies rub up against long-standing beliefs, and how millions of scientists and doctors failed to see what was right in front (and inside!) of their noses. We also find out how mapping the anatomy of this hidden infrastructure may help solve one of the fundamental mysteries of cancer, and perhaps provide a bridge between ancient and modern medicine.Special thanks to Aaron Wickenden, Jessica Clark, Mara Zepeda, Darryl Holliday, Dr. Amy Chang, Kate Sassoon, Guy Huntley, John Jacobson, Scotty G, and the Village Zendo
EPISODE CREDITS -
Reported by - Lulu Miller and Jenn BrandelProduced by - Matt Kieltywith help from - Ekedi Fausther-Keeyswith mixing help from - Arianne WackFact-checking by - Natalie Middletonand Edited by - Alex Neason
EPISODE CITATIONS -
Articles: Check out reporter Jenn Brandel’s companion essay to this episode in Orion magazine, titled, Invisible Landscapes (https://zpr.io/NKuxvYY84RvH), which argues that the discovery of the interstitium could challenge established practices of compartmentalizing in science and society.Our newsletter comes out every Wednesday. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)! Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today. Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.
Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
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Previous Episode

Funky Hand Jive
November 10, 2023
•30m
Back when Robert was kid, he had a chance encounter with then President John F. Kennedy. The interaction began with a hello and ended with a handshake. And like many of us who have touched greatness, 14 year old Robert was left wondering if maybe some of Kennedy would stay with him. Back in 2017, when this episode first aired, Robert found himself still pondering that encounter and question. And so with the help of what was brand new science back then, and a helping hand from Neil Degrasse Tyson, he set out to satisfy this curiosity once and for all.EPISODE CREDITS:Produced by - Simon Adlerwith help from - Only Human: Amanda Aronczyk, Kenny Malone, Jillian Weinberger and Elaine Chen.
EPISODE CITATIONS:
Videos:
The Handshake Experiment (https://zpr.io/buzgQeJJLqvY)Books: Neil deGrasse Tyson's newest book is called "Astrophysics for People in A Hurry." (https://zpr.io/idRcrMu3Kj8c) Ed Yong, “I Contain Multitudes.” (https://zpr.io/ff5imFP3kA6s)
Our newsletter comes out every Wednesday. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!
Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.
Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.
Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
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Next Episode

Shrink
November 24, 2023
•48m
The definition of life is in flux, complexity is overrated, and humans are shrinking.
Viruses are supposed to be sleek, pared-down, dead-eyed machines. But when one microbiologist stumbled upon a GIANT virus, hundreds of times bigger than any seen before, all that went out the window. The discovery opened the door not only to a new cast of microscopic characters with names like Mimivirus, Mamavirus, and Megavirus, but also to basic questions: How did we miss these until now? Have they been around since the beginning? What if evolution could go ... backwards?
In this episode from 2015, join former co-hosts Jad Abumrad and Robert Krulwich as they grill Radiolab regular Carl Zimmer on these paradoxical viruses – they’re so big that they can get their own viruses! - and what they can tell us about the nature of life.
Our newsletter comes out every Wednesday. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!
Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.
Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.
Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
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