Smart Brain Imaging to understand Dementia
Dementia Research Charity Chatathon
12/08/22
•30m
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Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Scott Mitchell, Alzheimer's Research UK Ambassador and widow of the incredible Dame Barbara Windsor along with researchers Dr Maura Malpetti, Race Against Dementia ARUK Fellow at University of Cambridge and Zeynep Şahin, PhD Student at King's College London.
Dr Maura Malpetti - My research focusses on inflammation in frontotemporal dementia and related disorders. I use innovative brain imaging techniques and blood tests to measure central and peripheral inflammation in people living with these conditions, relating these markers to clinical outcomes and other measures for disease progression (i.e. brain shrinkage, junk proteins etc).
Zeynep Şahin - Exploring the eye as the window to the brain, with imaging and machine learning: Can Optical coherence tomography (OCT) of the retinal structure and vasculature be used to diagnose and subtype prodromal neurodegenerative disease and visual neuropsychiatric symptoms.
Scott Mitchell - After graduating and taking on various TV and theatre roles, Scott met his future wife, actress Dame Barbara Windsor, who he shared his life with her for 27 years, before she passed away in 2020.
In 2014, Barbara was given the devastating news that she had been diagnosed with Alzheimer’s, a day that would change both hers and Scott’s lives forever. Although initially kept private, Scott and Barbara went public with the news in 2018. Scott was offered support and advice, entering the 2019 London Marathon with a team of Barbara’s friends and ex-cast mates from Eastenders, known as Barbara’s Revolutionaries. Alongside Alzheimer’s Research UK, Scott raised vital funds for Dementia Revolution. To date it is the record-breaking charity partner for the London Marathon, raising over £4 million. Scott also ran the 2021 marathon, again raising more money for ARUK, which he is now an ambassador for.
Most recently Scott was massivley influential in persuading the goverment provide an extra £95m for dementia research, and start the 'Babs Army' campaign to urge more people to sign up for clinical trials in the UK via Join Dementia Research.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia.
Raising money for research and providing insights into the latest research taking place across the UK and Worldwide. This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
Previous Episode
Clinical Trials, Lewy Bodies & what Sleep can tell us
December 8, 2022
•29m
Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Olga Borejko, Project Manager at King's College London and Victoria Grace Gabb, Research Associate at University of Bristol & Southmead Hospital
Olga Borejko - I manage a portfolio of clinical studies and commercial trials for patients with dementia with Lewy bodies (DLB) and Mild Cognitive Impairment (MCI) due to Alzheimer’s disease, at Old Age Psychiatry, King’s College London. I’m responsible for setting up the studies, recruitment and completing clinical/cognitive assessments with patients. My main research interest lies within understanding better how clinical and biological markers affect the disease trajectory in DLB patients. Specifically, how biomarkers associated with Alzheimer’s disease pathology affect the rate of cognitive decline in DLB patients (ENLIST-UK & EPND study, my PhD). At KCL, we are also involved in clinical trials looking at disease modifying treatments, which aim to reduce amyloid beta plaques in patients with prodromal AD (Abate study).
Victoria Gabb - I work at the Bristol Brain Centre in Southmead Hospital in sleep and dementia research, looking specifically at sleep and circadian rhythms in older adults during the early stages of Alzheimer's disease and Lewy body disease compared to older adults without cognitive impairment. A lot of the work we're doing at the moment is looking at how we can identify sleep and circadian changes in the home environment using technology such as actigraphy, EEG headbands, and mobile apps.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia.
Raising money for research and providing insights into the latest research taking place across the UK and Worldwide. This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
Next Episode
Detecting Dementias
December 9, 2022
•27m
Recorded at the Dementia Research Charity #Chatathon 2022 - Adam Smith interviews Dr Coco Newton, Research Fellow for EDoN at University College London and Jane Alty, Professor of Neurology & Consultant Neurologist at University of Tasmania.
Dr Coco Newton - I am a cognitive neuroscientist focused on finding ways to detect dementia earlier. In my PhD at the University of Cambridge, funded by the Alzheimer’s Society, I worked on challenging the assumption that memory decline is the first symptom of Alzheimer’s disease dementia - showing instead that navigation impairments may occur earlier. Currently I work as a research fellow within in the Alzheimer’s Research UK ‘Early Detection of Neurodegeneration’ (EDoN) initiative, identifying early-stage technologies that could provide personalised digital biomarkers of different dementia diseases.
Professor Jane Alty - I am an academic Neurologist (clinician researcher) specialising in cognitive and movement disorders. I am Co Director of the ISLAND cognitive assessment and research clinic (Tasmania, Australia). My research involves developing digital biomarkers of Alzheimers, Parkinsons and other neurological disorders.
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The 2022 Dementia Research Charity Chatathon LIVE was held on Friday 2nd December - A non-stop 12.5 hours livestream hosted by Adam Smith interviewing 68 Dementia Researchers and Special Guests working across all areas of discovery to beat Alzheimer's disease and all forms of dementia. Raising money for research and providing insights into the latest research taking place across the UK and Worldwide.
This year we are raising money for four amazing charities who all fund research - Alzheimer's Research UK, Alzheimer's Society, Race Against Dementia and The Lewy Body Society.
For more information and to donate visit http://www.chatathon.uk
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